Figure 3

Dependence of renal angiotensin converting enzyme 2 (ACE2) activity on protein concentration in the MF1 mouse. Effect of protein concentration on the time course of product formation in (A) male and (B) female mice. Data are representative of three experiments performed in triplicate. (C) Effect of protein concentration on product formation at 40 min in male and female mice; *P < 0.01 versus female by t-test; two-way ANOVA revealed a significant effect of protein (P < 0.0001) and sex (P < 0.0001) on renal ACE2 activity; n = 4/group.