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Table 1 Percent increase in response over control in male and female osteoblasts treated with 10-8M 1α,25(OH)2D3.

From: Sex dependent regulation of osteoblast response to implant surface properties by systemic hormones

   % Increase treatment versus control
Sex Surface Cell No. Alkaline Phosphatase Osteocalcin Osteoprotegerin Active TGF-β1 Latent TGF-β1
Male TCPS -4.6 92.5 41.5 185.9 111.8 154.8
  PT -11.3 94.7 37.0 219.9 256.4 162.8
  SLA -13.6 85.0 71.0 224.2 257.8 236.2
Female TCPS 0.3 45.7 17.3 172.1 81.8 60.7
  PT 0.2 43.9 20.5 184.8 77.6 98.8
  SLA -3.1 39.4 21.2 141.5 123.3 115.5
  1. TCPS, tissue culture polystyrene; PT, pretreated; SLA, grit-blasted/acid etched.